
La papaya fermentata è un integratore, ottenuto dalla papaya tramite un processo di fermentazione naturale che dura diversi mesi, al termine di questo processo la papaya viene macinata in una polvere finissima. I primi ricercatori che studiavano la papaya fermentata asserivano che i fitonutrienti contenuti nella papaya potessero rallentare moltissimo l'invecchiamento, combattendo i radicali liberi, una delle cause della degenerazione dell'organismo con l'età.
Riportiamo alcuni dei numerosi studi sugli effetti della papaya fermentata.
| 1. | Improved function of diabetic wound-site macrophages and accelerated wound closure in response to oral supplementation of a fermented papaya preparation. |
| Collard E, Roy S. | |
| Antioxid Redox Signal. 2010 Jan 23. [Epub ahead of print] | |
| PMID: 20095880 [PubMed - as supplied by publisher] | |
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| 2. | Decreased hemolysis following administration of antioxidant-fermented papaya preparation (FPP) to a patient with PNH. |
| Ghoti H, Rosenbaum H, Fibach E, Rachmilewitz EA. | |
| Ann Hematol. 2009 Sep 15. [Epub ahead of print] No abstract available. | |
| PMID: 19756600 [PubMed - as supplied by publisher] | |
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| 3. | Inhibitory effect of fermented papaya preparation on hydroxyl radical generation from methylguanidine. |
| Noda Y, Murakami S, Mankura M, Mori A. | |
| J Clin Biochem Nutr. 2008 Nov;43(3):185-90. Epub 2008 Oct 31. | |
| PMID: 19015753 [PubMed - in process] | |
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| 4. | Fermented papaya preparation as redox regulator in blood cells of beta-thalassemic mice and patients. |
| Amer J, Goldfarb A, Rachmilewitz EA, Fibach E. | |
| Phytother Res. 2008 Jun;22(6):820-8. | |
| PMID: 18384199 [PubMed - indexed for MEDLINE] | |
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| 5. | Nutraceutical strategy in aging: targeting heat shock protein and inflammatory profile through understanding interleukin-6 polymorphism. |
| Marotta F, Koike K, Lorenzetti A, Naito Y, Fayet F, Shimizu H, Marandola P. | |
| Ann N Y Acad Sci. 2007 Nov;1119:196-202. | |
| PMID: 18056967 [PubMed - indexed for MEDLINE] | |
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| 6. | [Association of antioxidants and natural immune activators in the treatment of astheno-teratospermia and abacterial leukocytosis] |
| Gambera L, Campanella G, Piomboni P, Serafini F, Morgante G, De Leo V. | |
| Minerva Ginecol. 2007 Oct;59(5):473-9. Italian. | |
| PMID: 17912173 [PubMed - indexed for MEDLINE] | |
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| 7. | Oxidative-inflammatory damage in cirrhosis: effect of vitamin E and a fermented papaya preparation. |
| Marotta F, Yoshida C, Barreto R, Naito Y, Packer L. | |
| J Gastroenterol Hepatol. 2007 May;22(5):697-703. | |
| PMID: 17444858 [PubMed - indexed for MEDLINE] | |
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| 8. | Tocopherol and tocotrienol levels of foods consumed in Hawaii. |
| Franke AA, Murphy SP, Lacey R, Custer LJ. | |
| J Agric Food Chem. 2007 Feb 7;55(3):769-78. | |
| PMID: 17263473 [PubMed - indexed for MEDLINE] | |
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| 9. | Comparative activity of antioxidants from wheat sprouts, Morinda citrifolia, fermented papaya and white tea. |
| Calzuola I, Gianfranceschi GL, Marsili V. | |
| Int J Food Sci Nutr. 2006 May-Jun;57(3-4):168-77. | |
| PMID: 17127467 [PubMed - indexed for MEDLINE] | |
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| 10. | Fermented papaya preparation attenuates beta-amyloid precursor protein: beta-amyloid-mediated copper neurotoxicity in beta-amyloid precursor protein and beta-amyloid precursor protein Swedish mutation overexpressing SH-SY5Y cells. |
| Zhang J, Mori A, Chen Q, Zhao B. | |
| Neuroscience. 2006 Nov 17;143(1):63-72. Epub 2006 Sep 8. | |
| PMID: 16962711 [PubMed - indexed for MEDLINE] | |
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| 11. | Plasma glucose level decreases as collateral effect of fermented papaya preparation use. |
| Danese C, Esposito D, D'Alfonso V, Cirene M, Ambrosino M, Colotto M. | |
| Clin Ter. 2006 May-Jun;157(3):195-8. | |
| PMID: 16900843 [PubMed - indexed for MEDLINE] | |
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| 12. | Molecular effects of fermented papaya preparation on oxidative damage, MAP Kinase activation and modulation of the benzo[a]pyrene mediated genotoxicity. |
| Aruoma OI, Colognato R, Fontana I, Gartlon J, Migliore L, Koike K, Coecke S, Lamy E, Mersch-Sundermann V, Laurenza I, Benzi L, Yoshino F, Kobayashi K, Lee MC. | |
| Biofactors. 2006;26(2):147-59. | |
| PMID: 16823100 [PubMed - indexed for MEDLINE] | |
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| 13. | Nutraceutical supplementation: effect of a fermented papaya preparation on redox status and DNA damage in healthy elderly individuals and relationship with GSTM1 genotype: a randomized, placebo-controlled, cross-over study. |
| Marotta F, Weksler M, Naito Y, Yoshida C, Yoshioka M, Marandola P. | |
| Ann N Y Acad Sci. 2006 May;1067:400-7. | |
| PMID: 16804018 [PubMed - indexed for MEDLINE] | |
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| 14. | Relationship between aging and susceptibility of erythrocytes to oxidative damage: in view of nutraceutical interventions. |
| Marotta F, Pavasuthipaisit K, Yoshida C, Albergati F, Marandola P. | |
| Rejuvenation Res. 2006 Summer;9(2):227-30. | |
| PMID: 16706649 [PubMed - indexed for MEDLINE] | |
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| 15. | [The Pope and the enlightenment of fermented papaya] |
| Nau JY. | |
| Rev Med Suisse. 2005 Feb 9;1(6):459. French. No abstract available. | |
| PMID: 15786653 [PubMed - indexed for MEDLINE] | |
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| 16. | [The Pope and the enlightenment of fermented papaya] |
| Nau JY. | |
| Rev Med Suisse. 2005 Feb 2;1(5):392. French. No abstract available. | |
| PMID: 15776806 [PubMed - indexed for MEDLINE] | |
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| 17. | Natural antioxidants may prevent posttraumatic epilepsy: a proposal based on experimental animal studies. |
| Mori A, Yokoi I, Noda Y, Willmore LJ. | |
| Acta Med Okayama. 2004 Jun;58(3):111-8. Review. | |
| PMID: 15471432 [PubMed - indexed for MEDLINE] | |
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| 18. | The aging/precancerous gastric mucosa: a pilot nutraceutical trial. |
| Marotta F, Barreto R, Tajiri H, Bertuccelli J, Safran P, Yoshida C, Fesce E. | |
| Ann N Y Acad Sci. 2004 Jun;1019:195-9. | |
| PMID: 15247013 [PubMed - indexed for MEDLINE] | |
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| 19. | [Immunology. Bolstering the immune system with the power of fermented papaya] |
| [No authors listed] | |
| Krankenpfl J. 2003;41(10-12):221. German. No abstract available. | |
| PMID: 14746200 [PubMed - indexed for MEDLINE] | |
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| 20. | Nitric oxide synthesis and TNF-alpha secretion in RAW 264.7 macrophages: mode of action of a fermented papaya preparation. |
| Rimbach G, Park YC, Guo Q, Moini H, Qureshi N, Saliou C, Takayama K, Virgili F, Packer L. | |
| Life Sci. 2000 Jun 30;67(6):679-94. | |
| PMID: 12659174 [PubMed - indexed for MEDLINE] | |
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| 21. | Tulimbe Nutrition Project: a community-based dietary intervention to combat micronutrient malnutrition in rural southern Malawi. |
| Berhe G. | |
| SCN News. 1997 Dec;(15):25-6. | |
| PMID: 12293177 [PubMed - indexed for MEDLINE] | |
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| 22. | Ferric nitrilotriacetate induced DNA and protein damage: inhibitory effect of a fermented papaya preparation. |
| Rimbach G, Guo Q, Akiyama T, Matsugo S, Moini H, Virgili F, Packer L. | |
| Anticancer Res. 2000 Sep-Oct;20(5A):2907-14. | |
| PMID: 11062700 [PubMed - indexed for MEDLINE] | |
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| 23. | Cyanocobalamin absorption abnormality in alcoholics is improved by oral supplementation with a fermented papaya-derived antioxidant. |
| Marotta F, Tajiri H, Barreto R, Brasca P, Idéo GM, Mondazzi L, Safran P, Bobadilla J, Idéo G. | |
| Hepatogastroenterology. 2000 Jul-Aug;47(34):1189-94. | |
| PMID: 11020912 [PubMed - indexed for MEDLINE] | |
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| 24. | Free radical scavenging activity of fermented papaya preparation and its effect on lipid peroxide level and superoxide dismutase activity in iron-induced epileptic foci of rats. |
| Imao K, Wang H, Komatsu M, Hiramatsu M. | |
| Biochem Mol Biol Int. 1998 Jun;45(1):11-23. | |
| PMID: 9635126 [PubMed - indexed for MEDLINE] | |
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